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Discover new advances
in neurostimulation

Pioneering a paradigm shift for ‘selective’ neural electrical stimulation

Core value of Neurinnov’s
ASIC neural stimulation platform

Restoring hand grasping movements in patients with complete tetraplegia will be the first of Neurinnov’s applications using its technology platform.

Mitigates side-effects

Mastering selective stimulation is the core of Neurinnov’s business. Its ‘generic’ technology platform can stimulate whichever nerve is required to restore or modulate a function while limiting undesired activation. Mitigating the side-effects that can be induced by a non-selective stimulation is the proof of value.

Neurinnov’s ASIC neural stimulation platform is targeting applications to:

Neurinnov’s
neurostimulator
will consist of:

An embedded ASIC, the key to achieving selective stimulation and the ability to guide the stimulation of a nerve

Casing surrounding the neurostimulator to which electrodes are connected

A controller connected to the implant via an external antenna. The wireless powering of and communication of data with the implanted device will be enabled by wireless transcutaneous energy transfer

Software with advanced interfaces to ease the tuning of the neuroprosthesis. Hand biomechanics are complex and selective stimulation is contra intuitive. The software embeds powerful algorithms that will overcome these issues

An intuitive patient interface that allows the user to control the whole system with discretion, preliminary assessed by patients: the learning curve was short and the efficiency was high.

Innovative device offering unique features:

The device will be able to:

Restoring hand movement
in patients with complete tetraplegia

Our implantable neurostimulator is specifically designed for a population of patients living with a complete tetraplegia who are ineligible for tendon transfer and orthopedic surgery, the only solutions available to date.

Neurinnov’s goal is to provide them with an implant through which they can control a desired hand movement by using one of four modalities to pilot the neurostimulator device. The patient will be able to choose to open a hand via:

Voice control based on a classical microphone
The contraction of supra-lesional muscles (EMG signals)
The movement of the contralateral shoulder, allowing the shoulder to be used as a joystick
Push button commands located on a headrest or armrest

Case study

Patients with complete tetraplegia regain use of hands

Two patients with complete tetraplegia, a condition of paralysis from the shoulders down, were once again able to grasp objects and perform everyday activities, such as holding a can or eating with fork, through the use of a neurostimulation device designed by Neurinnov under the AGILIS study, led by Inria.

Partnering in innovation

A strong caliber of partners is vital to enabling us to stretch our imaginations. Together, we search for new and improved approaches that advances technological developments in neurostimulation to bring real benefits to underserved medical populations.